Обложка книги NS-2710

NS-2710

ISBN: 978-6-1320-0423-9;
Издательство: Книга по требованию

NS-2710 (LS-193,970) is an anxiolytic drug with a novel chemical structure, developed by the small pharmaceutical company Neurosearch. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. NS-2710 is a potent but non-selective partial agonist at GABAA receptors, although with little efficacy at the ?1 subtype and more at ?2 and ?3. It has anxiolytic effects comparable to chlordiazepoxide,[1] and while it is a less potent anticonvulsant than the related drug NS-2664, it has a much longer duration of action, and similarly to other ?2/?3-preferring partial agonists produces little sedative effects or physical dependence.

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